riboxx is a biotech company with a unique expertise in design, engineering and GMP manufacturing of RNA (ribonucleic acid).
This expertise translates in two business lines: riboxx pharmaceuticals, and riboxx life sciences.
riboxx pharmaceuticals : unique immunotherapy drugs
riboxx pharmaceuticals develops and manufactures GMP TLR3 ligands for immunotherapy of cancer or virus diseases.
The drugs developed at riboxx pharmaceuticals act by triggering activation of the so called "innate immune system". The innate immune system is the first line of defense of the body. It is also the oldest immune defense strategy, and is found in all classes of animal life. It is a non-specific immune system, (i.e. not specific for one pathogen), being triggered by molecular patterns, such as double-stranded RNA (dsRNA).
Immune cells playing an important role in innate immunity include dendritic cells, macrophages, neutrophils, and Natural Killer cells. These cells are directly implicated in mounting a potent immune response to cancer or virus infections.
The drugs developed at riboxx belong to the class of Toll-like-Receptor 3 agonists (TLR3) and RIG-I-like-Receptor (RLR) agonists. The drug substance of these drugs is RNA (ribonucleic acid).
riboxx life sciences: reagents for research and development
riboxx life sciences develops customized and tailor-made molecular tools for gene knockdown in vitro and in vivo through RNA interference: small interfering RNA (siRNA) and microRNA (miRNA). RNA interference is a new technology broadly used in life science. With the help of RNA interference, genotype-phenotype correlation studies as well as identification of gene expression patterns are possible.